The specific detection of human blood in the faeces, so-called "hidden faecal bleeding", invisible to the naked eye, allows early detection of serious colorectal diseases. By combining a non-human-specific reaction with a human-specific reaction, the method can be used to reliably detect occult intestinal bleeding for screening purposes.
The FECA test detects the haemoglobin content of faecal blood on a guaiacol-impregnated filter paper based on a cumene-peroxide colour reaction. Identification from a sample with a positive colour reaction can be performed by the human-specific immunochemical method using the enclosed FOB test.